Working together: Farnesyl transferase inhibitors and statins block protein prenylation
نویسندگان
چکیده
منابع مشابه
Working together: Farnesyl transferase inhibitors and statins block protein prenylation.
Farnesyl transferase inhibitors (FTIs) have so far proved to have limited value as single agents in clinical trials. This PharmSight will focus on the use of a novel group of FTIs that are most effective in vitro when used in combination with the "statin" class of anti-hypercholesterolemic agents, which also block protein prenylation. We recently showed that these novel FTIs in combination with...
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ژورنال
عنوان ژورنال: Molecular and Cellular Pharmacology
سال: 2009
ISSN: 1938-1247
DOI: 10.4255/mcpharmacol.09.01